R Ketamine Nasal Spray - Unflavoured

 

How does Ketamine affect our brain and body?

Ketamine exerts various effects on brain receptors. Specifically, therapeutic doses target NMDA receptors, which are responsible for learning, memory, and emotional regulation. Studies have demonstrated that ketamine acts as an NMDA receptor antagonist, which lead to its antidepressant effects. Research published in The Journal of Neuroscience revealed that ketamine’s interaction with these receptors can provide rapid relief to patients suffering from treatment-resistant depression (TRD). It is ketamine’s blockage of NMDA receptors that promote the release of other neurotransmitters, such as dopamine and serotonin, which assist in mood regulation. For these reasons ketamine-assisted therapy  has shown to be successful in treating anxiety, trauma, and PTSD.

How to consume Ketamine?

Ketamine can be snorted, ground up and filled in capsules, or dissolved in water and swallowed.

How to be safe with Ketamine?

Before partaking in any substance it is always important to know what you are taking. Ketamine can often be cut with additives to alter the high produced. This can lead to various adverse health effects depending on the cut and the dosage. At Shopketamineonline we have all of our Ketamine tested to ensure its purity. Rest assured that all Ketamine is only of the purest quality to ensure your health and safety. Testing is done at www.getyourdrugstested.com. Please do your own research based on your own health conditions to understand if a substance will be safe for you.

Possible side effects of ketamine include:Disorientation and general confusion due to the drug’s anaesthetic nature,drowsiness, increased heart rate. elevated blood pressure.Large doses can result in what is called a “K-hole,” which can include intense visual and auditory hallucinations coupled with marked derealization and a detachment from reality.


(R)-Ketamine: Longer lasting and more potent antidepressant effects.
(S)- Ketamine: Stronger dissociative and psychedelic effects.
Recommended Dosage:
200mg to 300mg – Orally
30mg to 200mg – Intranasal

Orally VS Intranasal
Oral Bioavailability (16–20%): Generally considered a nicer experience, however due to the decrease in bioavailability a higher dosage is typically required.
Intranasal Bioavailability (45-50%): Higher bioavailability which will result in a stronger experience at lower doses and a quicker come up.